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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4S0590 | Columbin | Phospholipase , COX , Parasite | |
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. | |||
T27135 | DDD85646 | DDD 85646,DDD-85646 | Parasite |
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM. | |||
T63059 | CRK12-IN-1 | Antibiotic | |
CRK12-IN-1 is a potent CRK12 inhibitor.CRK12-IN-1 has insecticidal activity, with inhibitory effects on Trypanosoma brucei (T.b. brucei) and Trypanosoma congolense (T. congolense) with EC50s of 1.3 and 18 nM, respectivel... | |||
T3792 | Ajugol | Leonuride | Parasite |
Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml). | |||
T10340 | Antitrypanosomal agent 2 | Parasite | |
Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei. | |||
T23973 | DDD100097 | DDD 100097,DDD-100097 | Others |
DDD100097 is a potent N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders. | |||
T77551 | 6'-hydroxydihydrocinchonidine | Antibiotic , Drug Metabolite | |
6'-hydroxydihydrocinchonidine is a metabolite of quinine, with antimicrobial and antitumor activity, and inhibitory effect on Trypanosoma brucei and Streptococcus pneumoniae. | |||
T77645 | JC-229 | TRP/TRPV Channel | |
JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT). | |||
T2112 | Fexinidazole | HOE 239 | Others , Parasite |
Fexinidazole (HOE 239) is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologica... | |||
T2S1792 | Lycobetaine | Ungeremine | Antibacterial |
1. Lycobetaine (Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Lycobetaine have strong antibacterial activity against Flavobacterium columnare . 3. Lycobetaine effectively... | |||
T23132 | Pentamidine dihydrochloride | MP-601205 dihydrochloride | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi... | |||
T69764 | NPD-008 | ||
NPD-008 is an inhibitor of trypanosoma brucei phosphodiesterase B1 (TbrPDEB1). | |||
T69765 | NPD-039 | ||
NPD-039 is an inhibitor of trypanosoma brucei phosphodiesterase B1 (TbrPDEB1). | |||
TN2485 | 1,2-Dihydrotanshinone | 1,2-Dihydrotanshinquinone | Antifection |
1,2 Dihydrotanshinquinone is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum. | |||
T13223 | Tuberculosis inhibitor 1 | Others | |
Tuberculosis inhibitor 1 is a potent and non-cytotoxic inhibitor of trypanosoma brucei growth (EC50: 5 nM). | |||
TN3220 | 7',8'-Dihydroobolactone | Antifection | |
7',8'-Dihydroobolactone can inhibit Trypanosoma brucei brucei with an IC(50) of 2.8 microM. | |||
T6769 | Elaiophylin | Efomycin E,Gopalamicin,Salbomycin,Azalomycin B | Others , Autophagy |
Elaiophylin (Salbomycin) shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively. | |||
T12286 | Obtusifoliol | Others | |
Obtusifoliol is a specific inhibitor of CYP51(Trypanosoma brucei (TB) and human CYP51 with Kd values of 1.2 µM and 1.4 µM, respectively). | |||
T69313 | Ascofuranone | ||
Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH. | |||
T61912 | TbPTR1 inhibitor 1 | ||
TbPTR1 inhibitor 1 (compound 5d) is an effective inhibitor of kinetochore pteridine reductase 1 (PTR1). The IC50 of TbPTR1 inhibitor 1 inhibits Trypanosoma brucei PTR1 (TbPTR1) is <0.1 nM, EC50 of TbPTR1 inhibitor 1 inhi... |